Abstract Geographic atrophy is an eye disease that greatly interferes with the daily lives of patients and their families, posing a serious threat to the aging European demographic.Over the past 30 months, this initiative has assembled leading experts in the field of ophthalmology to share insights on the necessary policy steps that need to be take
It is widely accepted that gene expression regulation is a stochastic event.The common approach for its computer simulation requires detailed information on the interactions of individual molecules, which is often not available for the analyses of biological experiments.As an alternative approach, we employed a more intuitive model to simulate the
Abstract Background Astrocytes (AC) are essential for brain homeostasis.Much data suggests that AC support and protect the vascular endothelium, but increasing evidence indicates that during injury conditions they may lose their supportive role resulting in endothelial cell activation and BBB disturbance.Understanding the triggers that flip this sw